Blog | Select Ingredients

What Are Mushroom Extract Ratios? The Truth About Potency & Quality

Written by Chris Burdick | Tue, Jun 17 2025

Mushroom supplements often boast high extraction ratios like 10:1 or 15:1 on their labels. At first glance, these ratios sound impressive, implying a highly concentrated product. But what do they really mean, and do they guarantee a quality extract? This post will demystify mushroom extract ratios, explain why ratio-based claims can be misleading, and highlight the real criteria that determine extract quality. Whether you’re a product formulator, brand manager, or an educated supplement consumer, understanding these nuances will help you make informed decisions and avoid marketing traps. By the end, you’ll see why moving beyond the hype of ratios is crucial, and how BeyondMushrooms is leading the way with transparency and scientifically validated quality.

Jump to Section:

What Are Mushroom Extracts Ratios (and How Are They Calculated)?

An extraction ratio, 10:1, 15:1, 30:1, and so on, compares the weight of starting mushroom material to the weight of the final powdered extract. Brands typically highlight these numbers as a quick way to communicate how concentrated or “potent” their ingredient is. For example, a 10:1 ratio indicates that ten kilograms of raw material were used to yield one kilogram of finished extract. 

Below are the two main ways suppliers generate those impressive-looking ratios.

1. Water-Weight Inflation

Fresh mushrooms are 90–95 % water. If you harvest 10kg of fresh Lion’s Mane, dry it overnight, and mill it, you’re left with roughly 1kg of plain dry powder, already a “10:1” shrinkage without concentrating anything. Some suppliers quietly use this fresh-weight basis to claim big ratios:

Stage Operation Typical Weight Shift What Happens to Actives
Harvest Pick fresh mushrooms (≈90-95% water) 10 kg → 10 kg Actives are highly diluted in water
Drying Air or low-heat drying removes moisture 10 kg → ≈ 1 kg Only water leaves; beta-glucans stay at the same concentration per gram of dry matter
Label Math Supplier divides 10kg by 1kg Prints “10:1” (or 12:1, 20:1) Ratio reflects dehydration, not enrichment

Key Point: An extract ratio calculated this was is just moisture loss; no concentration of beta-glucans or other actives. 

2. Dry-Powder Solvent Extraction

More reputable processors start with already-dried mushroom powder and then use hot water, alcohol, or dual solvents to pull out specific fractions (beta-glucans, triterpenes, etc.). This process typically reduces material while concentrating bioactive compounds:

Stage Operation Typical Weight Shift What Happens to Actives
Load Add 10 kg of pre-dried mushroom powder to extractor 10 kg → 10 kg Starting beta-glucans often 10–20 % (species-dependent)
Extract Hot water, alcohol, or dual solvent pulls soluble polysaccharides & triterpenes 10 kg → liquid slurry Insoluble chitin, starch, grain substrate left behind
Concentrate & Dry Filter, evaporate solvent, then spray-dry Slurry → ≈ 1 kg concentrated powder Beta-glucans can climb to 20-40% if process is optimized
Label Math Supplier divides 10kg by 1kg (or 15kg by 1kg, etc.) Prints “10:1”, “15:1”, “30:1” Same-looking ratio, but actual potency depends on extraction conditions

Key Point: A solvent-based ratio can deliver a richer extract, yet two “15:1” powders may differ wildly because species, solvent, temperature, and filtration all influence the final beta-glucan number. Only lab assays (for example, the AOAC Megazyme beta-glucan test) confirm real strength.

How Brands Utilize Ratio Numbers on the Label

Once an ingredient supplier provides a 10:1 or 15:1 extract, many consumer brands translate that ratio into eye-catching milligrams on the front of the package.

See the two images below from a top-selling Cordyceps gummy on Amazon:

The first splashy graphic shouts “500 mg Cordyceps”, but the Supplement Facts panel tells the real story: 50mg of a 10:1 Cordyceps militaris extract. On paper the math converts 50mg of extract into a “500mg” headline, yet the label supplies zero information about the actual active compounds. Unless you spot that fine-print “10:1,” you’ll assume you’re getting ten times more mushroom (and far more actives) than the product truly provides.

Does that glossy ratio really tell the whole story of what ends up in your formula, or just decorate the label? Up next, we’ll unpack why leaning on ratios alone can send you off course and reveal the metrics that give a far clearer picture of mushroom quality.

Why Ratio-Based Marketing Is Misleading

Relying on mushroom extract ratios as a measure of quality can lead brands and consumers astray. Here are the key reasons ratio-based claims often fall short of the truth:

  1. Ratios Reveal Northing About Bioactive Content
    A numeric ratio reveals nothing about the levels of active ingredients (like beta-glucans, the famous immune-supporting polysaccharides). You can have a 10:1 extract that’s mostly inert material if the extraction process didn’t actually capture the bioactive compounds. What matters is the content of functional molecules, not just how much raw material went in. The medicinal value of mushrooms is largely tied to beta-1,3/1,6-glucans and other actives, which a simple ratio does not measure. Potency lives in analytical numbers, not arithmetic.
  2. No Common Rulebook
    There is no unified standard for calculating ratios. One producer starts with fresh weight, another uses dried powder, a third runs a dual-solvent extraction. This lack of consistency means one brand’s “15:1” might not be equivalent to another’s. A high ratio claim can be more about marketing optics than substance when every manufacturer sets their own rules.
  3. Potency Isn’t Linear
    It’s tempting to assume a 10:1 extract is ten times more potent than a 1:1. Reality is more complex. Extraction is not 100% efficient - you might start with 10 kg of mushroom, but that doesn’t mean all the actives end up in the 1 kg extract. Different compounds extract at different rates, and some are lost or left behind. Without knowing the extract's composition, the ratio can mislead you into thinking its stronger than it really is. Thus, a higher ratio doesn’t automatically translate to proportional efficacy. 
  4. “High Polysaccharides” ≠ High Beta-Glucans
    Mushroom marketers often tout high polysaccharide content, implying high beta-glucans. But “polysaccharides” is an umbrella term; it can include non-beneficial sugars like starch (alpha-glucan) from grain fillers. Some products, especially those made from mycelium grown on grain, test high in polysaccharides but low in the mushroom’s unique beta-glucans. In fact, independent analyses have found supplements with impressive polysaccharide numbers that turned out to be mostly starch, offering little medicinal value. Brands may conflate total polysaccharides with beta-glucans to sound potent, when in truth a large portion might be inactive alpha-glucans. Without specific testing, a “50% polysaccharide” claim could mean mostly grain starch, hardly the immune support you’re looking for.

"Relying solely on a simple ratio indicator is not enough to assess the quality of a medicinal mushroom food supplement. To obtain meaningful information, it is essential to have a detailed breakdown of the bioactives on the label." - Anna Zozulia, HIFAS da TERRA.

In summary, a ratio is a poor proxy for quality. It tells us nothing about what matters most: the presence and quantity of actual bioactive compounds. High ratios can be achieved through water weight loss or over-concentration of filler substances. Smart consumers and formulators should look beyond the ratio and ask: What’s really in this extract?

What to Look for in a Quality Mushroom Extract

If ratios aren’t reliable, how do we gauge a mushroom extract’s quality? Here are the key factors to consider when evaluating or formulating a mushroom-based product:

1. Quantified Bioactive Content

Extraction only matters if you can prove how much β-1,3/1,6-glucan or other target molecules end up in the drum. Beta-glucans are the critical active compounds linked to immune modulation and other benefits. Look for testing by the AOAC-approved Megazyme method, which is the industry gold standard for measuring mushroom beta-glucans. This assay distinguishes beta-glucans from alpha-glucans, so you know you’re getting real mushroom actives rather than starch. According to experts, any mushroom ingredient that doesn’t list beta-glucan content (verified by this method) should be questioned. In short, ignore flashy ratio claims, check the beta-glucan assay results instead.

Metric to Confirm Why It Matters Good Benchmark
β-1,3/1,6-glucan % (Megazyme method) Core immune-modulating compound 20%+ acceptable, 50%+ premium
Alpha-glucan % (Inert polysaccharides)  High values imply grain/starch filler <5%
Lab performing test Third-party ISO 17025 lab avoids bias Independent COA for every lot

2. Human (or Robust Pre-Clinical) Evidence

If you plan on making impactful structure-function claims (“supports immune response,” “improves focus”), you should have evidence on the exact material you’re purchasing. Reference studies alone won't let you claim "clinically proven" benefits; at best they support soft "may help" language. The best scenario is when the extract has been evaluated in randomized controlled trials (RCTs) or published human studies demonstrating its efficacy for certain health outcomes. This shows that the product delivers real benefits at a given dose. When reading supplier info or marketing, note whether they provide studies on their exact extract (e.g., “our Reishi extract was shown in a human study to improve immune markers”). 

Checklist:

  • Study population matches your target consumer (e.g., healthy adults vs. clinical cohort)
  • Published in a peer-reviewed journal or has a whitepaper pending publication
  • Uses the commercial ingredient by brand name and discloses daily dose
  • Reports objective endpoints (e.g., NK-cell activity, cognitive scores) with stats

3. Formulation Performance

Even a potent extract is useless if it ruins taste, sediments, or degrades in processing. Confirm three practical traits: solubility, stability, and sensory impact. A good powder dissolves well in hot and cold water, survives pasteurization or baking, and contributes minimal bitterness or color so you’re not forced to bury it under sugar.

Attribute Primary Drivers Why It Matters in Your Formulation
Solubility Insoluble cell-wall material (chitin, insoluble α-glucans) and grain starch resist hydration; extracts rich in water-soluble β-1,3/1,6-glucans disperse easily. Clear RTDs, stick packs, and gummies stay smooth, no grit or settling that turns consumers off.
Stability High protein or amino-sugar fractions denature and darken under heat or low pH, while carbohydrate-rich β-glucans remain stable. Survives pasteurization, baking, candy cooking; potency and flavor stay intact without overdosing.
Sensory Impact Residual proteins, phenolic complexes, and triterpenes drive harsh taste and dark color; fine filtration removes these. Reduces need for bitter blockers or extra sugar; finished products taste cleaner and keep a simpler label.

4. Regulatory Compliance (GRAS Status)

GRAS status is the difference between a mushroom extract you can use in food and one that might trigger a recall. FDA-notified GRAS provides a public “no-objection” letter, whereas self-affirmed GRAS relies on a private expert panel. With FDA signaling tighter oversight of self-affirmed dossiers, an FDA-reviewed extract is the safest bet. Learn more about GRAS here.

GRAS Path Who Reviews? Public Record? Audit Risk
FDA-notified GRAS FDA Toxicologists Yes (GRAS inventory) Low
Self-affirmed GRAS Company-paid consultants No Medium
No GRAS - - High (food use blocked in many retailers)

Tip: Ask your supplier for the GRAS details. A top-tier extract will proudly share that it’s FDA-reviewed (if applicable), or at minimum provide a thorough safety dossier.

Quick Litmus Test

  1. Does the extract list beta glucan 1,3/1,6 content (Megazyme-verified)?
  2. Is there human data at your intended daily dose?
  3. Is the extract soluble, heat-stable, and workable in taste?
  4. Is the extract FDA-notified GRAS (or at least in the process of doing so)?

In summary, a quality mushroom extract is defined by its composition and evidence, not by an arbitrary ratio. Look for high verified beta-glucan content, credible research backing, good formulation characteristics, and solid regulatory standing. These are the markers of an extract that will deliver real value and efficacy.

BeyondMushrooms: Setting the Gold Standard

Now that we've unpacked why mushroom ratios alone don’t reflect real quality, let’s look at how BeyondMushrooms provides exactly what savvy formulators, brand managers, and educated consumers should demand from their mushroom extracts:

  1. Verified Potency and Transparency
    Every batch of BeyondMushrooms is standardized to deliver ≥70% beta-1,3/1,6-glucans, confirmed by third-party Megazyme testing. Rather than leaning on ambiguous ratios or generic "polysaccharide" claims, BeyondMushrooms supplies hard, verifiable data on the bioactives that actually matter.
  2. Clinically Proven at Low Doses
    Unlike brands that rely on general mushroom studies or reference materials, BeyondMushrooms invests in randomized controlled trials using the exact extract and dosage you'll use:

    These trials let you confidently use structure-function claims ("supports memory and cognitive health," "enhances immune response") rather than vague "may support" statements.

  3. Exceptional Formulation Flexibility
    BeyondMushrooms powders are engineered for seamless integration into almost any product type. They're 100% water-soluble; no gritty residue or clumping in beverages, stick packs, or gummies. The extracts maintain stability across extreme heat and varying pH levels, safeguarding potency during pasteurization, baking, or acidic formulations. Advanced filtration ensures zero bitterness and a neutral flavor profile, eliminating the need for excessive sweeteners or bitter-maskers.
  4. Unmatched Regulatory Assurance (FDA-Notified GRAS)
    BeyondMushrooms stands alone as the only mushroom extract line to hold FDA-notified GRAS status. Unlike self-affirmed GRAS, BeyondMushrooms' safety and compliance have been openly reviewed and accepted by the FDA, offering total transparency and peace of mind. As regulatory scrutiny intensifies, partnering with an FDA-vetted ingredient future-proofs your product and simplifies label claims.

Leading with Integrity, Not Ratios

While BeyondMushrooms could easily leverage extraction ratios to create sensational marketing claims ("50:1" or higher), we deliberately avoid this tactic. The goal is clear: shift industry focus from meaningless ratios to verified potency, proven clinical outcomes, real-world performance, and regulatory clarity.

Conclusion

In the booming world of functional mushrooms, knowledge is indeed power. We’ve seen that mushroom extract ratios, while simple and enticing, often mislead more than they inform. A high ratio might simply reflect water loss, basic drying, or selective math, not genuine potency and quality. What truly defines a quality mushroom extract are the concrete measures of its active components, backed by science and appropriate safety oversight. Educated formulators and consumers should demand to see beta-glucan percentages, specific testing methods, human trial data, and regulatory credentials. These factors separate the genuine, effective products from the gimmicky ones.

For food, beverage, and supplement brands looking to incorporate mushrooms, the choice is clear: align with ingredients and partners that uphold these factors. Not only will you be offering a better product, but you’ll also be contributing to a more honest marketplace.

In the end, cutting through the ratio hype leads to better decisions and better health outcomes. By focusing on what really matters - true potency, evidence-based dosing, safety, and functionality - brands can create mushroom products that earn consumer trust. And consumers, armed with this understanding, can confidently select products that deliver on their promises. Beyond the misleading ratios lies a world of genuinely effective mushroom nutrition, and that’s where the smart money (and smart science) is.